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Swallowing dysfunction in adult patients with Chiari I malformation – CSF Flow

Swallowing dysfunction in adult patients with Chiari I malformation

Background

Swallowing difficulties have been reported in patients with Chiari I malformation (CMI) with a prevalence of 4-47%, but existing evidence is based only on case reports. We aimed to prospectively study swallowing function in adult patients with CMI before and three months after surgical decompression.

Methods

We included all adult patients diagnosed with Chiari I malformation from September 2015 to October 2017 who underwent a planned surgery at Sahlgrenska University Hospital, Sweden. The patients were offered the opportunity to participate in and undergo an assessment consisting of the “Watson Dysphagia Scale (WDS)” and “EORTC QLQ-OG25” written questionnaires in addition to videofluoroscopic examination of swallowing (VFS) before and 3 months after surgery. Demographic data and comorbidities were recorded.

Results

Eleven patients were included, nine of which underwent both pre- and postoperative evaluations. Four patients (36%) reported varying degrees of swallowing complaints (mean WDS score, 16). In two of these, there was substantial penetration of contrast material into the laryngeal vestibule on VFS, and in the other two patients, minor swallowing disturbances were observed. Borderline deviations from normal VFS findings were also found in three asymptomatic patients. Although not all VFS deviations completely disappeared after surgery, the patients reported no remaining symptoms.

Conclusion

Symptoms of dysphagia and objective abnormalities on VFS are not uncommon in CMI patients. Surgery has the potential to remedy underlying causes of dysphagia, thereby relieving its symptoms.